1

Jerry L. Workman

Member of the National Academy of   Sciences and the American Academy of Arts and Sciences

Stowers Institute in the United   States

Genetics and Developmental   Biology

His   exceptional contributions to gene expression research have reshaped the   field, particularly in uncovering the pivotal role of histones in DNA   packaging and gene regulation.

2

Don W. Cleveland

Member of the National Academy of   Sciences and the American Academy of Arts and Sciences

University of California, San   Diego

Genetics and Developmental   Biology

He   has conducted pivotal research in elucidating the molecular pathogenesis of   hereditary ALS, and has made groundbreaking contributions to the assembly of   mitotic spindles and the regulation of chromosome movement.

3

Tak Wah Mak

Member of the National Academy of   Sciences

University of Toronto

Genetics and Developmental   Biology

He   has made the initial discovery of T-cell TCR receptors and having contributed   numerous pioneering works to immunology.

4

Philip A. Beachy

Member of the National Academy of   Sciences and the American Academy of Arts and Sciences

Stanford University

Genetics and Developmental   Biology

He   is a world leading developmental biologist. He discovered how Cyclopamine and   Smoothened are related to Itraconazole, thus linking diverse fields of   scientific research.

5

Liqun Luo

Member, of National Academy of   Sciences

Stanford University

Genetics and Developmental   Biology

He   is a world leading neurobiology biologist. He made distinguished   contributions to neural development, neural network construction, and   technological development in systems neuroscience. His research on synaptic   branching in the context of establishing and maintaining neural circuits is   at the international leading frontier.

6

Jin Billy Li

Professor

Stanford University

Genetics and Developmental   Biology

An   internationally renowned RNA biologist, he revealed the core function of RNA   editing in distinguishing “self” from “non-self” nucleic acids. This work   provided a key mechanism for understanding how the innate immune system   avoids reacting to its own genome.

7

Katrin Andreasson

Professor

Stanford University School of   Medicine

Genetics and Developmental   Biology

She   has identified innate immune pathways critical in establishing neurotoxic   immune responses that lead to neurodegeneration in models of aging, AD, and   stroke.

8

Qiang Liu

Professor

University of Science and   Technology of China

Genetics and Developmental   Biology

He   has long been engaged in research on learning and memory, neurodegenerative   diseases, and brain aging, with a focus on elucidating the mechanisms of   epigenetic regulation in these processes. In recent years, he has achieved a   series of significant research findings.

9

Xiaoguang Lei

Professor

Peking University

Genetics and Developmental   Biology

He   focus on chemical biology, translational medicine, synthetic biology, and   innovative drug development targeting major human diseases. He first proposed   and validated a novel bio-catalytic strategy distinct from existing methods,   achieving transformative biosynthesis of amide bonds, thereby providing a   precise, green, and efficient catalytic solution for biomanufacturing—a   strategic emerging industry.

10

Guangshuo Ou

Professor

Tsinghua University

Genetics and Developmental   Biology

His   research is dedicated to cytoskeleton and cilia biology, where he has made a   series of breakthroughs in the mechanisms of asymmetric cell division,   directed cell migration, and ciliogenesis. The synthetic data-driven methods   he developed, such as SynSeg, have revolutionized the quantitative segmentation   and analysis of subcellular structures.

11

Kang Zhang

Member of the Academia Europaea

Wenzhou Medical University

Genetics and Developmental   Biology

Ranked   first in China in the field of ophthalmology among the global top 100,000   scientists, Professor Zhang Kang has achieved numerous pioneering   accomplishments in cutting-edge areas such as ocular genetic diseases,   artificial intelligence-assisted ophthalmic diagnosis, and stem cell therapy.

12

Feng Zhang

Professor

Sun Yat-sen University

Genetics and Developmental   Biology

He   has long been engaged in research on the circulatory system, focusing on   elucidating the regulatory mechanisms of vascular and lymphatic endothelial   function and discovering innovative therapeutic approaches for ocular   vascular and lymphatic system disorders.

13

Ming Xu

Professor

Peking University

Genetics and Developmental   Biology

His   research focuses on the molecular mechanisms of heart failure, particularly   the regulation of excitation-contraction coupling in cardiomyocytes during   heart failure. He has identified key molecules and their upstream regulators   responsible for the structural disorganization and functional decline of   cardiomyocyte excitation-contraction coupling.

14

Jing Qu

Professor

Chinese Academy of Sciences

Genetics and Developmental   Biology

By   integrating research in stem cell biology, epigenetics, and metabolic   biology, she has revealed the mechanisms underlying chromatin structural   changes and metabolic instability associated with cellular senescence, and has   elucidated their pathophysiological effects during the aging of tissues and   organs.

15

Li Jin

Member of the Chinese Academy of   Sciences (CAS)

Fudan University

Evolutionary and Computational   Biology

He   is a leading scientist of the model of recent African origin of modern humans   and the study of human phenomics. His research encompasses genetic structure   and migrations of human populations, genetics of human complex diseases and   computational biology.

16

Mark Stoneking

Member of the National Academy of   Sciences (NAS)

Max Planck Institute for   Evolutionary Anthropology

Evolutionary and Computational   Biology

Prof.   Stoneking is a geneticist and molecular anthropologist whose work has   significantly advanced our understanding of human evolution. Through   pioneering studies of mitochondrial DNA, he provided crucial evidence for the   African origin of modern humans and illuminated the concept of Mitochondrial   Eve, representing the most recent common maternal ancestor of all living   people.

17

Chung-I Wu

Member of the National Academy of   Taiwan

Sun Yat-sen University

Evolutionary and Computational   Biology

He   has pioneered the study of speciation at the molecular level, introducing   cutting-edge gene replacement techniques to answer classical ecological questions   in the model organism Drosophila. He also made original contributions in   areas such as selfish genes, molecular clocks, X chromosome degeneration, and   evolutionary genomics.

18

Jian Yang

Professor

Westlake University

Evolutionary and Computational   Biology

Professor   Jian Yang has long been dedicated to research in statistical genetics,   genomics, and the genetic mechanisms underlying complex traits. He is an   internationally recognized scholar in the fields of complex trait   heritability analysis and genomic big-data methodology. His team has   developed widely used analytical methods and software, including GCTA, SMR,   and OSCA, and has made important contributions to understanding the genetic   basis of complex traits and major diseases, population health, multi-omics   data analysis, and precision medicine.

19

Ting Wang

Professor

Washington University in St.   Louis

Evolutionary and Computational   Biology

His   lab developed widely-used DNA methylomics technologies and applies integrated   methods combining experimental and computational techniques to study the   evolution and adaptation of human regulatory networks.

20

Jianzhi Zhang

Professor

University of Michigan

Evolutionary and Computational   Biology

Professor   Jianzhi Zhang is a Marshall W. Nirenberg Collegiate Professor of University   of Michigan. He is a renowned scholar in the field of molecular and genome   evolution,

He   has made a series of pioneering contributions to the study of natural   selection, gene duplication, fitness landscapes, gene pleiotropy, genetic   interactions, mutation rates, transcriptome evolution, and synonymous codon   usage. He has published approximately 250 papers, which have been cited over   25,000 times.

21

Xuegong Zhang

Professor

Tsinghua University

Evolutionary and Computational   Biology

Professor   Xuegong Zhang is a prominent scholar in the fields of bioinformatics and   machine learning, and a Fellow of the International Society for Computational   Biology (ISCB Fellow). He has made significant contributions to   transcriptomics analysis, single-cell bioinformatics, the construction of the   Human Cell Atlas, and the mechanisms of gene expression regulation, with   hundreds of publications to his name.

22

Guojie Zhang

Professor

Zhejiang University

Evolutionary and Computational   Biology

His   research primarily focuses on biodiversity genomics, with an emphasis on the   origins and adaptation mechanisms of species, organismal-level   macroevolutionary processes and their underlying molecular drivers, as well   as the evolution and development of complex biological traits. As a leading   scholar in the field of global biodiversity genomics, he has initiated and   led several major international life science mega-projects, including the Bird   10,000 Genomes (B10K) Project. He has made pioneering, globally impactful   contributions to reconstructing the tree of life and unraveling the molecular   evolutionary principles of complex traits.

23

Guillaume Bourque

Professor

McGill University

Evolutionary and Computational   Biology

Prof. Bourque is a leading computational biologist and   genomicist whose research focuses on the function and evolution of mammalian   genomes. He has made influential contributions to our understanding of   transposable elements, gene regulation, structural variation, and genome   rearrangements in evolution and cancer. His group also develops widely used   computational tools and genomic annotation resources that support large-scale   genomics research and precision medicine initiatives worldwide.

24

Kai Ye

Professor

Xi’an Jiaotong University

Evolutionary and Computational   Biology

Professor Kai Ye has long been dedicated to research in genomic   structural variation, biomedical big data, artificial intelligence   algorithms, and precision medicine. He is among the early researchers to   apply next-generation sequencing technologies to genomic studies. He has   participated as a key member in major international scientific projects,   including the 1000 Genomes Project, the International Cancer Genome   Consortium, and The Cancer Genome Atlas. His work has made important   contributions to structural variation analysis, cancer genomics, pangenomics,   and digital medicine.

25

Zhiwei Cao

Professor

Fudan University

Evolutionary and Computational   Biology

Zhiwei   Cao focuses on the development of computational methods for new therapeutics.   She has constructed SEPPA methods for B-cell epitope prediction, CE Blast   method for cross protective measurement between conformational epitopes for   newly emerged pathogens. Meanwhile, she also pioneered the TCM data platfrorm   for “herbal recipe herbs-compounds- in   vivo metabolites -molecular targets” and established a   highacurate method for multi-component drug synergy prediction.

26

Shuhua Xu

Professor

Fudan University

Evolutionary and Computational   Biology

He   has long been committed to the study of human population genomics, developing   and applying population genomics methods and computational biology tools to   apply population genetics and molecular evolutionary theories to the study of   adaptive evolution and disease mechanisms. He has organized and promoted   large-scale population genomics research projects such as the China   Populationome Consortium (CPC) and the Han Chinese 100,000 Genomes Project   (Han100K).

1

Jerry L. Workman

院士

美国斯托瓦斯研究所

遗传与发育生物学

揭示组蛋白在DNA包装成染色质和基因表达调控中的关键作用，在基因表达研究领域做出了里程碑式贡献。

2

Don W. Cleveland

院士

加州大学圣地亚哥分校

遗传与发育生物学

著名肿瘤学和神经生物学家，阐明遗传性ALS分子发病机制方面的关键研究，及有丝分裂纺锤体的组装和染色体运动的调控方面开创性工作。

3

Tak Wah Mak院士

多伦多大学

遗传与发育生物学

世界知名的免疫学基因和癌症基因领域专家，首次发现T细胞TCR受体，并在免疫学方面做出多项开创性工作。

4

Philip A. Beachy院士

斯坦福大学

遗传与发育生物学

世界领先的发育生物学家，在发育生物学和癌症研究方面做出了许多重要贡献，特别是在肝细胞癌（HCC）的研究中，他的工作对于理解HCC的发病机制和治疗具有重要意义。

5

骆利群院士

斯坦福大学

遗传与发育生物学

在神经发育、神经网络的构建与组织神经科学的技术开发方面做出了卓越贡献，突触分枝以建立和维持神经回路领域的研究处于国际领先水平。

6

李进教授

斯坦福大学

遗传与发育生物学

国际知名的RNA生物学家，揭示了RNA编辑在区分“自我”与“非我”核酸中的核心功能，为理解先天免疫系统如何避免对自身基因组产生反应提供了关键机制。

7

Katrin Andreasson

教授

斯坦福大学医学院

遗传与发育生物学

揭示了在衰老、阿尔茨海默病和中风模型中建立导致神经退行性的神经毒性免疫反应的关键先天免疫途径。

8

刘强教授

中国科学技术大学

遗传与发育生物学

长期从事学习记忆，神经退行性疾病以及脑衰老等方面的研究工作，并致力于解析表观遗传调控在脑衰老和神经退行性疾病中的作用机制。近年来取得了一系列重要研究成果。

9

雷晓光教授

北京大学

遗传与发育生物学

主要研究方向是针对人类重大疾病的化学生物学、转化医学、合成生物学与创新药物开发。首次提出并验证了一种不同于既有方法的全新生物催化策略，实现了酰胺键的变革性生物合成，为生物制造这一战略性新兴产业提供了精准、绿色、高效的催化利器。

10

欧光朔教授

清华大学

遗传与发育生物学

致力于细胞骨架与纤毛生物学研究，在不对称细胞分裂、定向细胞迁移及纤毛发生机理方面取得系列突破，开发的SynSeg等合成数据驱动方法，革新了亚细胞结构的定量分割与分析。

11

张康院士

温州医科大学

遗传与发育生物学

张康教授在全球顶尖前10万科学家排名中位居“中国眼科领域第一名”，在眼遗传病、人工智能辅助眼科诊断、干细胞治疗等前沿领域取得了众多开创性成果。

12

张峰教授

中山大学

遗传与发育生物学

长期在循环系统领域从事科研工作，致力于研究血管和淋巴管内皮功能调控机制和发现眼血管和淋巴系统病变的创新治疗手段。

13

徐明教授

北京大学

遗传与发育生物学

研究方向为心力衰竭（心衰）的分子机制，重点围绕心衰中心肌细胞兴奋收缩耦联调控机制开展研究，发现导致心肌细胞兴奋收缩耦联结构紊乱和功能衰退的关键分子及其上游调控分子，成果获国家发明专利授权，并在临床检测中得到验证。

14

曲静教授

中国科学院动物研究所

遗传与发育生物学

结合干细胞、表观遗传及代谢生物学研究，揭示了细胞衰老的染色质结构演变与代谢失稳机制，阐明了其在组织器官衰老过程中的病理生理效应。

15

金力院士

复旦大学

进化与计算生物学

近代人类非洲起源模型和人类表型组学研究的领先科学家。对第二代遗传标记的群体遗传学理论和方法、连锁不平衡形成机制及其在疾病基因定位中的应用等领域做出了重要贡献，并在东亚人群的遗传结构、群体分化、迁徙路线、人群混合和环境适应等方面的研究取得了重大成果。

16

Mark Stoneking

院士

马克斯·普朗克进化人类学研究所

进化与计算生物学

国际著名遗传学家和分子人类学家，在人类起源与演化研究领域作出重要贡献。其早期线粒体DNA研究为现代人非洲起源学说提供了关键证据，并推动了“线粒体夏娃”概念的建立，深刻影响了现代分子人类学的发展。

17

吴仲义院士

中山大学

进化与计算生物学

率先在遗传学实验的基础上把物种形成研究带入分子层次，首先在模式动物果蝇的研究中引入尖端基因取代技术来解答生态学问题。同时在自私基因、分子钟、X染色体退化及进化基因组学等领域的研究也取得了独创性成果。

18

杨剑教授

西湖大学

进化与计算生物学

长期致力于统计遗传学、基因组学和复杂性状遗传机制研究，是国际上复杂性状遗传力解析和基因组大数据方法学研究领域的重要学者。其团队发展了 GCTA、SMR、OSCA 等广泛应用的分析方法和软件，在复杂性状与重大疾病遗传基础解析、群体健康、多组学数据分析和精准医学等领域取得了重要成果。

19

王艇教授

圣路易斯华盛顿大学

进化与计算生物学

开发了广泛使用的DNA甲基组学技术，并应用结合实验和计算技术的综合方法来研究人类调节网络的进化和适应，特别是这些过程对人类健康和疾病的影响。

20

张建之教授

密歇根大学

进化与计算生物学

张建之博士是美国密歇根大学第一位Marshall W. Nirenberg讲席教授。他在自然选择、基因复制、适应度地形、基因多效性、基因互作、突变率、转录组进化以及同义密码子使用率等领域做出了系列开创性贡献。

21

张学工教授

清华大学

进化与计算生物学

张学工博士是生物信息学和机器学习领域的杰出学者。他在转录组学分析、单细胞生物信息学、人类细胞图谱的构建以及基因表达调控机制等方面做出了重要贡献。

22

张国捷教授

浙江大学

进化与计算生物学

研究主要聚焦于生物多样性基因组学，重点关注物种的起源与适应机制、个体层面的宏观进化过程及其背后的分子驱动因素，以及复杂生物性状的进化与发育机制。作为国际生物多样性基因组学领域的领军学者，他发起并主导了“万种鸟类基因组计划（B10K）”等多项国际生命大科学工程，在重构物种生命之树及解析复杂性状分子演化规律方面做出了具有全球影响力的开创性贡献。

23

Guillaume Bourque教授

麦吉尔大学

进化与计算生物学

国际知名的计算生物学与基因组学专家，致力于解析哺乳动物基因组的功能与演化机制。他率先揭示了转座子在基因调控和基因组进化中的重要作用，并在结构变异、基因组重排与癌症基因组学研究方面作出重要贡献。同时，他开发了多项大规模基因组数据分析工具和功能注释资源，为现代基因组学研究和精准医学发展提供了关键技术支撑。

24

叶凯教授

西安交通大学

进化与计算生物学

长期致力于基因组结构变异、生物医学大数据、人工智能算法和精准医学研究，是较早接触并应用第二代高通量测序技术开展基因组学研究的学者之一，曾作为主要成员参与千人基因组计划、国际肿瘤基因组计划、美国肿瘤基因组图谱计划等国际重大科学工程。其团队发展了多种基因组变异检测与多组学数据分析方法，在结构变异解析、癌症基因组学、泛基因组学和数字医学等领域取得了重要成果，为推动基因组学研究从数据解析走向精准医学应用做出了重要贡献。

25

曹志伟教授

复旦大学

进化与计算生物学

研究聚焦于抗体设计与多组分协同用药的计算模型，建立了抗原表位预测-免疫交叉反应计算-抗体虚拟筛选平台，并在国际上率先建立了“复方-中药-成分-代谢-靶点”数据资源共享平台，研发了分子靶点发现与多成分协同药效预测模型，实现了中药作用机制自动解析。

26

徐书华教授

复旦大学

进化与计算生物学

长期致力于人类群体基因组学研究，发展和运用计算生物学手段，将群体遗传学和分子进化理论应用于适应性演化和疾病发生机制研究；组织和推动了中国人群泛基因组联盟（CPC）、亚洲人群泛基因组联盟（APC）、汉族十万人基因组计划（Han100K）等大型合作研究项目。